Mesothelioma Causes Disease

Working with asbestos is the major risk factor for mesothelioma. In the United States, asbestos is the major cause of malignant mesothelioma and has been considered to be "denied" associated with the development of mesothelioma. Indeed, the relationship between asbestos and mesothelioma was so strong that many consider mesothelioma is a "signal" or "sentinel" tumor. The history of asbestos exposure exists in many cases. However, mesothelioma has been reported in some individuals without any known exposure to asbestos. In rare cases, mesothelioma has also been associated with irradiation, intrapleural thorium dioxide (Thorotrast), and inhaling other fibrous silicates, such as erionit. Some studies suggest that simian virus 40 (SV40) may act as a cofactor in the development of mesothelioma.

Asbestos was known in ancient times, but it was not mined and widely used commercially until the late 19th century. Its use greatly increased during World War II. Since the early 1940s, millions of American workers have been exposed to asbestos dust. Initially, the risks associated with exposure to asbestos is not publicly known. However, the increased risk of developing mesothelioma was later found among shipyard workers, people working in asbestos mines and mills, producers of asbestos products, workers in the heating and construction industries, and other traders. Currently, the official position of the U.S. Occupational Safety and Health Administration (OSHA) and U.S. EPA is that the protection and "permissible exposure limits" required by United States regulations, while sufficient to prevent non-malignant asbestos-related mostly, they are inadequate to prevent or protect against asbestos-related cancers such as mesothelioma. Likewise, the British Government Health and Safety Executive (HSE) states formally that any threshold for mesothelioma must be at a very low level and is widely agreed that if any such threshold exists at all, so this time can not be measured. For practical purposes, therefore, HSE assumes that no such "safe" threshold exists. Others have noted also that there was no evidence of a threshold below which there is no risk of mesothelioma. There appears to be, linear dose-response relationship, with increasing doses of disease produces increased. [14] However, mesothelioma may be associated with a short, low-level or direct exposure to asbestos. The dose required for the effect seems to be lower for asbestos-caused mesothelioma than pulmonary asbestosis or lung cancer. Again, there is no known safe level of asbestos exposure associated with an increased risk of mesothelioma.

The duration of exposure mesothelioma asbestos so as to short. For example, cases of mesothelioma have been documented with only 1-3 months after infection. People who work with asbestos wear personal protective equipment to reduce risk exposure.

Latency, time from first exposure to manifestation of the disease, which is prolonged in the case of mesothelioma. This is almost never less than fifteen years and peak at 30-40 years. In a review of occupationally-related mesothelioma cases, the average latency is 32 years old. Based on data from Peto et al, the risk of mesothelioma appears to be rising third or fourth power of the first exposure.

1. Environmental exposures

The incidence of mesothelioma had been found to be higher in populations living near naturally asbestos. For example, in the heart of Cappadocia, Turkey, mesothelioma causes 50% of all deaths in three small villages - Tuzköy, Karain and Sarıhıdır. Initially, this is due erionit, a zeolite mineral with properties similar to asbestos, however, recently, detailed epidemiological investigations indicate that cause erionit mesothelioma mostly in families with genetic predisposition. Documented presence of asbestos fibers in water supplies and food products has prompted concerns about possible long-term impact and, as yet, unknown exposure of the general population of these fibers.

2. Job

Exposure to asbestos fibers has been recognized as an occupational health hazard since the early 20th century. Numerous epidemiological studies have linked exposure to asbestos with the development of pleural plaques, pleural thickening spreads, asbestosis, carcinoma of the lung and larynx, gastrointestinal tumors, and malignant pleural mesothelioma spreads and peritoneum. Asbestos has been widely used in industrial products, including cement, brake linings, gaskets, roofing shingles, flooring products, textiles, and insulation.

Commercial asbestos mining at Wittenoom, Western Australia, occurred between 1945 and 1966. A cohort study of miners working at the mine reported that while no deaths occurred within the first 10 years after crocidolite exposure, 85 deaths due to mesothelioma had occurred in 1985. In 1994, reported 539 deaths from mesothelioma have been reported in Western Australia.

3. secondary exposure Paraoccupational

Family members and others living with asbestos workers have an increased risk of developing mesothelioma, and possibly other diseases related to asbestos. These risks may result from exposure to asbestos dust brought home on clothing and hair of asbestos workers. To reduce the possibility of showing the family members to asbestos fibers, asbestos workers are usually required to shower and change their clothing before leaving the workplace.

4. Asbestos in buildings

Many building materials used in both public and domestic places before the banning of asbestos may contain asbestos. They work doing renovations or DIY activities may expose themselves to asbestos dust. In the UK the use of Chrysotile asbestos was banned in late 1999. Brown and blue asbestos was banned in England around 1985. Buildings built or renovated prior to these dates may contain asbestos materials.

3 Comment:

Mesothelioma said...

When asbestos is banned then why are they still using it they must need to avoid using of asbestos.

Ricky Mik said...
This comment has been removed by the author.
Ricky Mik said...

What are your odds of survival after being diagnosed with Mesothelioma??

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